The cees dekker Diaries

The cees dekker Diaries

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2009, discovery of a different phenotype for micro organism in slender nanofluidic slits; and to start with detection of local protein structures along DNA using sound-point out nanopores

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For a individual, I possess the biblical assignment to check out and use all the things in creation for the benefit of my neighbour. I tend not to working experience any conflict in between faith and science. On the contrary, my religion stimulates me to try and do science, to become open-minded on this planet.’

Deposition and atomic pressure microscopy of specific phthalocyanine polymers amongst nanofabricated electrodes

Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart style in 2005. (nl)

SMC complexes can move Bodily roadblocks bigger than their ring size, indicating a nontopological system for DNA loop extrusion

We use nanofabricated microfluidic constructions to pattern spatial boundaries for microorganisms and biomimetic vesicles with reconstituted protein networks and this assess the fundamental role of spatial confinement in the molecular and cellular amount. Our jobs ceesdekker include the subsequent:

Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is shown in gray, the rim from the pore is highlighted in pink, as well as a 3D rendering of your movement of the DNA rod is shown.

The rotors harness Power from the nanoscale drinking water and ion movement that is created by a static chemical or electrochemical likely gradient inside the nanopore, which are established via a salt gradient or applied voltage, respectively. These synthetic nanoengines self-Arrange and work autonomously in physiological ailments, suggesting approaches to constructing Strength-transducing motors at nanoscale interfaces.

Bulk-area coupling identifies the mechanistic relationship between Min-protein patterns in vivo and in vitro

Screening pseudotopological and nontopological products for SMC-driven DNA loop extrusion in opposition to roadblock-traversal experiments

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2013, controlled shaping of Are living bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations in the handedness of histone tetrasomes